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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 16.97
Human Site: S80 Identified Species: 28.72
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 S80 T L E D N R T S K A C P E H S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 S80 T L E D N R T S K A C P E H S
Dog Lupus familis XP_532204 495 54438 S80 T L A D N R T S K E C A E H S
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 S80 T L T D N R T S K E C A E H S
Rat Rattus norvegicus Q7TSF2 588 64736 V101 C N L G V A I V E M V N N S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 S74 A P V R A R C S S P I P A G E
Chicken Gallus gallus NP_001026257 484 53539 T78 V C P E H S S T I N V P R N T
Frog Xenopus laevis Q6INC8 576 63887 V88 C N L G V A I V S M V N N N T
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 V101 C N L G V A I V E M V N N N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 E80 A I K S G E A E E Y D D E C G
Honey Bee Apis mellifera XP_395682 508 56831 V79 V N L S V A I V A M T A E V R
Nematode Worm Caenorhab. elegans Q03567 493 52719 W78 S V I G E F D W D K Q T T G M
Sea Urchin Strong. purpuratus XP_780445 542 58846 T83 D M V N S T T T V N S T Q I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 F142 V L L C F S S F L L C N M D R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 80 N.A. 80 0 N.A. 20 6.6 0 0 N.A. 6.6 6.6 0 13.3
P-Site Similarity: 100 N.A. 100 80 N.A. 80 13.3 N.A. 20 46.6 13.3 20 N.A. 26.6 6.6 13.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 8 0 8 29 8 0 8 15 0 22 8 0 0 % A
% Cys: 22 8 0 8 0 0 8 0 0 0 36 0 0 8 0 % C
% Asp: 8 0 0 29 0 0 8 0 8 0 8 8 0 8 0 % D
% Glu: 0 0 15 8 8 8 0 8 22 15 0 0 43 0 8 % E
% Phe: 0 0 0 0 8 8 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 29 8 0 0 0 0 0 0 0 0 15 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 29 0 % H
% Ile: 0 8 8 0 0 0 29 0 8 0 8 0 0 8 0 % I
% Lys: 0 0 8 0 0 0 0 0 29 8 0 0 0 0 0 % K
% Leu: 0 36 36 0 0 0 0 0 8 8 0 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 29 0 0 8 0 8 % M
% Asn: 0 29 0 8 29 0 0 0 0 15 0 29 22 22 0 % N
% Pro: 0 8 8 0 0 0 0 0 0 8 0 29 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % Q
% Arg: 0 0 0 8 0 36 0 0 0 0 0 0 8 0 15 % R
% Ser: 8 0 0 15 8 15 15 36 15 0 8 0 0 8 36 % S
% Thr: 29 0 8 0 0 8 36 15 0 0 8 15 8 0 29 % T
% Val: 22 8 15 0 29 0 0 29 8 0 29 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _